Sam G. Raney, Sharareh Senemar, Matt Burke, Christina Lee, Jaimin R. Shah, Kevin S. Li, Om Anand, Kevin S. Warner

Correspondence should be addressed to: Margareth R. C. Marques, Senior Principal Scientist, US Pharmacopeia, 12601 Twinbrook Parkway, Rockville, Maryland, 20852–1790; email: mrm@USP.org.

Quality and performance testing of topical and transdermal products encompasses a broad set of product types, test equipment, and unique considerations. This Stimuli article is one in a series of such articles on product testing methods that explore the relevant considerations and identify opportunities for standardization with different types of quality and performance tests. The objective of this Stimuli article is to highlight current knowledge gaps and potential challenges associated with quality and performance tests for certain topical and transdermal products, and to stimulate public input from product testing labs, product developers, regulators, and others. The input received may inform the development or revision of USP general chapters.