BRIEFING

  〈89.1〉 Collagenase I. This proposal is based on the version of the chapter official as of May 1, 2017. This chapter is being revised to replace the specified dilution range mentioned for the Standard solution, i.e., 1:50 to 1:100 (v/v), in the Assay with "an appropriate dilution to achieve the absorbance range of 0.3–0.9 from the Analysis".

 Additionally, minor editorial changes have been made to update the chapter to current USP style.

 The comment period for this revision ends on November 30, 2025. In the absence of any significant adverse comments, it is proposed to implement this revision via an Interim Revision Announcement with an official date of March 1, 2026.

 (BIO2: K. Chandra)

 Case ID—SUB-2222