DEFINITION

Scaffold Silk Fibroin is a surgical scaffold device made from the silk of the Bombyx Mori silkworm. Raw silk filaments are comprised of a fibroin protein core that is naturally coated with the globular protein sericin. The sericin is removed from the fiber by aqueous extraction leaving the fibroin protein behind, consisting of layers of anti-parallel beta sheets, which give the fiber strength. The fiber is then assembled into a three dimensional patterned scaffold. The scaffold is a mechanically strong, flexible, single use device that can be produced in a variety of shapes, sizes, and thicknesses, and is terminally sterilized.