DEFINITION

Spironolactone Compounded Oral Suspension contains NLT 90.0% and NMT 110.0% of the labeled amount of spironolactone (C₂₄H₃₂O₄S). Prepare Spironolactone Compounded Oral Suspension 5 mg/mL in Ora-Blend as follows (see Pharmaceutical Compounding—Nonsterile Preparations 〈795〉). Crush the Spironolactone tablet(s) to a fine powder, and pass through a 40-mesh sieve. Wet the powder with a small amount of Ora-Blend, and triturate to make a smooth paste. Add the Ora-Blend to make the mortar contents pourable. Transfer the contents stepwise and quantitatively to a calibrated container using the remainder of the Ora-Blend. Add sufficient Ora-Blend to bring to final volume and mix well.