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Fondaparinux Sodium
C31H43N3O49S8Na10 1728.08
α-d-Glucopyranoside, methyl O-2-deoxy-6-O-sulfo-2-(sulfoamino)-α-d-glucopyranosyl-(1→4)-O-β-d-glucopyranuronosyl-(1→4)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-α-d-glucopyranosyl-(1→4)-O-2-O-sulfo-α-l-idopyranuronosyl-(1→4)-2-deoxy-2-(sulfoamino)-, 6-(hydrogen sulfate), decasodium salt;
Methyl O-2-deoxy-6-O-sulfo-2-(sulfoamino)-α-d-glucopyranosyl-(1→4)-O-β-d-glucopyranuronosyl-(1→4)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-α-d-glucopyranosyl-(1→4)-O-2-O-sulfo-α-l-idopyranuronosyl-(1→4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-α-d-glucopyranoside, decasodium salt [114870-03-0]

DEFINITION

Fondaparinux Sodium is the sodium salt of a synthetic sulfated pentasaccharide anticoagulant based on the antithrombin binding moiety of heparin. It is synthesized from a natural source of chirally pure sugars (mono- and di-saccharides). A range of coupling, (de)protection and functionalization reactions leads to crude fondaparinux sodium, which is further purified to yield the drug substance. Fondaparinux Sodium contains NLT 95.0% and NMT 103.0% of fondaparinux sodium, calculated on the anhydrous and solvent-free basis. Fondaparinux Sodium is a white to off-white powder.

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