INTRODUCTION

Topical aerosol products contain the drug in solution or in suspension, packaged under pressure, and released upon activation of an appropriate valve system. The topical aerosol products should follow the product quality test requirements described in general test chapters Inhalation and Nasal Drug Products—General Information and Product Quality Tests 〈5〉, Microbial Enumeration Tests 〈61〉, Tests for Specified Organisms 〈62〉, Minimum Fill 〈755〉, and Leak Rate 〈604〉. The topical aerosols include dermatological foams and sprays. Topical aerosol foams should include a physical appearance of both the foam and also of the collapsed foam.