Ivermectin
C48H74O14 (Component H2B1a)
875.09
C47H72O14 (Component H2B1b) 861.07
Component H2B1a:
Avermectin A1a, 5-O-demethyl-22,23-dihydro-.
(2aE,4E,8E)-(5′S,6S,6′R,7S,11R,13R,15S,17aR,20R,20aR,20bS)-6′-(S)-sec-Butyl-3′,4′,5′,6,6′,7,10,11,14,15,17a,20,20a,20b-tetradecahydro-20,20b-dihydroxy[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′-[2H]pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-l-arabino-hexopyranosyl)-3-O-methyl-α-l-arabino-hexopyranoside
[70161-11-4] Component H2B1b:
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-.
(2aE,4E,8E)-(5′S,6S,6′R,7S,11R,13R,15S,17aR,20R,20aR,20bS)-3′,4′,5′,6,6′,7,10,11,-oxospiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′[2H]pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-l-arabino-hexopyranosyl)-3-O-methyl-α-l-arabino-hexopyranoside [70209-81-3]
C47H72O14 (Component H2B1b) 861.07
Component H2B1a:
Avermectin A1a, 5-O-demethyl-22,23-dihydro-.
(2aE,4E,8E)-(5′S,6S,6′R,7S,11R,13R,15S,17aR,20R,20aR,20bS)-6′-(S)-sec-Butyl-3′,4′,5′,6,6′,7,10,11,14,15,17a,20,20a,20b-tetradecahydro-20,20b-dihydroxy[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′-[2H]pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-l-arabino-hexopyranosyl)-3-O-methyl-α-l-arabino-hexopyranoside
[70161-11-4] Component H2B1b:
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-.
(2aE,4E,8E)-(5′S,6S,6′R,7S,11R,13R,15S,17aR,20R,20aR,20bS)-3′,4′,5′,6,6′,7,10,11,-oxospiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′[2H]pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-l-arabino-hexopyranosyl)-3-O-methyl-α-l-arabino-hexopyranoside [70209-81-3]
» Ivermectin is a mixture of avermectin A1a, 5-O-demethyl-22,23-dihydro-(component H2B1a), and avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-(component H2B1b). It contains not less than 95.0 percent and not more than 102.0 percent for the sum of component H2B1a plus component H2B1b, calculated on the anhydrous and alcohol- and formamide-free basis; and the ratio (calculated by area percentage) of component H2B1a/(H2B1a + H2B1b) is not less than 90.0 percent. It may contain small amounts of suitable antioxidant and chelating agents.