C153H225N43O49S 3482.80
Glucagon (Human) [16941-32-5]

Glucagon is a polypeptide hormone that has the property of increasing the concentration of glucose in the blood. It has the same structure (29 amino acids) as the hormone produced by the α-cells of the human pancreas. Glucagon is produced from either synthetic or microbial processes using recombinant DNA (rDNA) technology. When produced by microbial processes, the host cell–derived protein content and/or the host cell–derived or vector–derived DNA content are determined by validated methods. During the course of product development, it must be demonstrated that the manufacturing process produces Glucagon having a biological activity of NLT 0.80 USP Units/mg, using a validated bioassay approved by a competent authority. It contains NLT 90% and NMT 105% of glucagon (C153H225N43O49S), calculated on the anhydrous basis.

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USP Glucagon (Human) RS
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