BRIEFING

 Lorazepam Compounded Injection. Because there is no existing USP monograph for this compounded preparation, a new monograph based on a validated stability-indicating method used to assess stability is proposed. The liquid chromatographic procedure in the Assay is based on analyses validated using the Phenomenex brand of analytical column with L1 packing. The typical retention time for lorazepam is about 4.0 min.

 Please submit comments to CompoundingSL@usp.org.

 (CMP: B. Groat)

 Case ID—SUB-660