BRIEFING

 Bupivacaine Hydrochloride Compounded Injection. Because there is no existing USP monograph for this compounded preparation, a new monograph based on a validated stability-indicating method for assessing stability is proposed. The liquid chromatographic procedure in the Assay is based on analyses validated using the Kinetex brand of analytical column with L1 packing. The typical retention time for bupivacaine hydrochloride is about 7.5 min.

 Please submit comments to CompoundingSL@usp.org.

 (CMP: B. Groat)

 Correspondence Number—C324024