BRIEFING

 Lidocaine and Tetracaine Compounded Topical Cream. Because there is no existing USP monograph for this compounded preparation, a new monograph is being proposed based on a validated stability-indicating method used to assess stability. The liquid chromatographic procedure in the Assay is based on analyses validated using the Sunfire C8 brand of column with L7 packing. The typical retention times for lidocaine and tetracaine are 26.4, and 28.3 min, respectively.

 Please submit comments to CompoundingSL@usp.org.

 (CMP: B. Groat)

 Correspondence Number—C316455