USPUSP-NF
This is a preview of
USP-NF/PF content.
Subscriber?
Access here!
Not a subscriber?
Learn more!
Calcium with Vitamin D Chewable Gels

BRIEFING

Calcium with Vitamin D Chewable Gels. A new USP monograph for this dietary supplement dosage form is being proposed.

  1. The liquid chromatographic procedure for the Strength assay for Vitamin D (Cholecalciferol), Method 1 is based on analyses performed with the 25-cm × 4.6-mm Hypersil-C18 brand of column with L1 packing. The approximate retention times for ergocalciferol and cholecalciferol are 12.6 and 13.4 min, respectively.

  2. The liquid chromatographic procedure for the Strength assay for Vitamin D (Cholecalciferol), Method 2 is based on analyses performed with the 25-cm × 4.6-mm Partisil brand of column with L3 packing. The approximate retention time for cholecalciferol is 10 min.

  3. The liquid chromatographic procedure for the two tests for vitamin D (cholecalciferol) in the Disintegration and Dissolution test is based on analyses performed with the 3-mm × 15-cm Ultimate AQ-C18 brand of column with L1 packing. The approximate retention time for cholecalciferol is 12.5 min.

 (NBDS: N. Davydova)

 Case ID—SUB-433

USP REFERENCE STANDARDS FOR PURCHASE

USP Cholecalciferol RS
USP Ergocalciferol RS
This is a preview of
USP-NF/PF content.
Subscriber?
Access here!
Not a subscriber?
Learn more!