BRIEFING

 Ketamine Compounded Cream. Because there is no existing USP monograph for this compounded drug product, a new monograph based on a validated stability-indicating method is being proposed. The liquid chromatographic procedure in the Assay is based on analyses validated using the Gemini C18 brand of column with L1 packing. The typical retention time for ketamine hydrochloride is about 15.3 min.

 Please submit comments to CompoundingSL@usp.org.

 (CMP: S. Mitiche)

 Correspondence Number—C299367