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Silicified Microcrystalline Cellulose

DEFINITION

Silicified Microcrystalline Cellulose is composed of intimately associated microcrystalline cellulose and colloidal silicon dioxide particles, derived from aqueous coprocessing prior to drying the material during manufacture. The microcrystalline cellulose component is purified, partially depolymerized cellulose, prepared by treating alpha cellulose, obtained as a pulp from fibrous plant material, with mineral acids. The colloidal silicon dioxide is a submicroscopic fumed silica prepared by the vapor-phase hydrolysis of a silicon compound. The Residue on Ignition result indicates the percentage of colloidal silicon dioxide; the remainder is microcrystalline cellulose.

USP REFERENCE STANDARDS FOR PURCHASE

USP Silicified Microcrystalline Cellulose RS
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