DEFINITION

Cascara Sagrada is the dried bark of Frangula purshiana (DC.) A.Gray [syn. Rhamnus purshiana DC.] (Fam. Rhamnaceae). It yields NLT 7.0% of the total hydroxyanthracene derivatives, calculated as cascaroside A and calculated on the dried basis. NLT 60% of the total hydroxyanthracene derivatives consists of cascarosides, calculated as cascaroside A.