DEFINITION

Carboxymethylcellulose Sodium Compounded Intraperitoneal Solution, Veterinary contains NLT 80.0% and NMT 120.0% of the labeled amount of carboxymethylcellulose sodium (C₈H₁₅NaO₈). Prepare Carboxymethylcellulose Sodium Compounded Intraperitoneal Solution, Veterinary 10 mg/mL (1%) as follows (see Pharmaceutical Compounding—Sterile Preparations 〈797〉). Wet the Carboxymethylcellulose Sodium with the Propylene Glycol in a suitable container. Place 450 mL of Sterile Water for Injection in a calibrated container on a hot plate with a stir bar and heat to NMT 100° (do not allow to boil). Add the Carboxymethylcellulose Sodium and Propylene Glycol mixture to heated Sterile Water for Injection by pouring along the outer edge of the water level and not directly into the vortex created by the stir bar to avoid clumping. Continue heating and stirring to facilitate complete dissolution of the Carboxymethylcellulose Sodium. Once completely dissolved, bring to final volume with Sterile Water for Injection. Transfer to a 500-mL high-density polyethylene (HDPE) plastic single-dose container suitable for autoclaving and crimp seals tightly before autoclaving. Sterilize by autoclaving.