DEFINITION

Calcitonin Salmon is a polypeptide that has the same sequence as that of the hormone that regulates calcium metabolism and is secreted by the ultimobranchial gland of salmon. It is produced from either synthetic processes or microbial processes using recombinant DNA (rDNA) technology. The host cell-derived protein content and the host cell- or vector-derived DNA content of Calcitonin Salmon produced from an rDNA process are determined by validated methods. It contains NLT 90.0% and NMT 105.0% of calcitonin salmon, calculated on an acetic acid-free and anhydrous basis.