BRIEFING

 Guarana Seed Dry Extract. This proposal is based on the version of the monograph official as of November 1, 2020. On the basis of comments received, the following revisions are being proposed:

1. Eliminate the use of Standard solution C in the Content of Caffeine and Flavonoids test.

2. Add the use of USP Caffeine RS in Standard solution B in the Content of Caffeine and Flavonoids test.

3. Add Table 2 to include the approximate relative retention times of the different analytes.

 Additionally, minor editorial changes have been made to update the monograph to current USP style.

 (BDSHM: M. Monagas)

 Case ID—SUB-3128